Nora and Tamara are two sisters who survive in a working class neighborhood of the coast. In the midst of a troubled adolescence, Nora's fragile relationship with the world around her is affected by the criminal environment in which her older sister lives.

Alfredo gathers all his friends for one night to tell them his best-kept secret: he's immortal.

In an unexpected encounter, the life of an experienced writer takes an unforeseen turn when he meets Fernando Lara, a peculiar hotel receptionist with an unusual medical condition. Fernando suffers from irritable bowel syndrome, a disease that basically makes him soil himself at any moment and in any circumstance throughout the day. This will lead him to a great adventure.