In a world where minds can be analysed for potential threats of crime and mental instability, Inspector Tsunemori Akane is sent to deal with her first case, along with fellow inspector Ginoza and a group of Enforcers, latent criminals hired by the police to work for them. Akane’s case deals with an insane man who has taken a woman hostage and raped her, holing himself up in a building inhabited by...

While Kogami is recuperating from Akane’s Paralyzer shot, she begins to worry about whether she is suited to be an Inspector after the fallout from her first case. On her second day on the job, she begins to learn more about the Enforcers she works with.

Ginoza and Akane, along with the Enforcers, are brought in to investigate a death caused by a Drone at a Drone manufacturing plant. When the Psycho-Pass of the entire staff checks out, they question whether it was an accident or possibly murder.

When the CID is brought in to investigate a disappearance of Kimihiko Hayama, they discover that not only has he been killed, but someone has taken over his net avatar, Talisman. The CID tries to track down the fake Talisman in order to find the killer.

The CID’s hunt for Kimihiko Hayama’s killer leads them to another murder with the same modus operandi. Now it’s up to the CID to figure out how to track down the killer’s real identity and get justice for the victims.

After reading Kogami’s personnel file, Akane attempts to learn more about Kogami’s past and why he ended up as an Enforcer. Meanwhile, the CID detectives attempt to figure out who was helping Kanehara commit murders in the Hachioji Drone incident.

After realizing that the recent murders and the Specimen Case are indeed connected, Ginoza takes Kogami off the case and requests Tsunemori to watch over him. Tsunemori discusses Sasayama's murder with Kogami, and he gives her his one piece of evidence: a blurry image of Makishima. Meanwhile, Makishima, in a study with another older man, reveals the circumstances of Rikako Oryo's father's death an...

With his profiling skills, Kogami determines that the girls' school killer isn't the same murderer from the unsolved case years ago; he explains that the recent murders lack "originality" and pointed social commentary of the previous killings. When he and Tsunemori realize the culprit is one of the students, they locate Rikako - who escapes when one of teachers stops Kogami from executing her. As ...

Kogami, attempting to track down Makishima, takes Tsunemori to visit his former teacher, Jouji Saiga, who agrees to give her a crash course on criminal profiling; however, Ginoza reprimands her harshly which results into an argument. Afterwards, Masaoka explains to her Ginoza's attitude by revealing his past. In the meantime, Makishima discusses humanity and philosophy with Senguji, who in an earl...

Makishima and Senguji set up a hunt by using Tsunemori's friend Yuki as bait to lure Kogami into an abandoned subway station. Upon entering the station, Kogami discovers Yuki and loses contact with Tsunemori; the two must evade Senguji and his canine drones as a curious Makishima observes from above. Ginoza scolds Tsunemori for letting Kogami go on his own but Masaoka chastises him over his treatm...

With a drone delivering him a Dominator, Kogami manages to outwit Senguji and kill him, although he also takes some shots in the process. Just then, Yuki is captured by Makishima, with Kogami too weak to follow. As Masaoka tends to Kogami's injuries, Tsunemori goes alone to pursue Makishima. To her shock, she discovers her Dominator is useless against him as his Crime Coefficent levels are too low...

Taking place three years prior to the series, the episode focuses on Yayoi, who was a guitarist in a band before being imprisoned in a rehabilitation facility for being a latent criminal. As she anxiously waits for release so she can play the guitar again, she is approached by Kogami, who was still a detective, and Ginoza about a series of crimes occuring in the area she was once familiar with. Sh...

Ginoza meets up with the head of the Public Security Bureau about Makishima, who confidentially reveals to him about the real culprit of the Specimen Case, Touma Kouzoburou, three years ago who happens to be "criminally asymptomatic" just like Makishima. She urges him to keep any doubts away from the public eye and orders him to capture Makishima. Following Yuki's funeral, Akane agrees to undergo ...

A man in a helmet breaks into a pharmacy, kills the staff, and departs with drugs. When the MWSPB arrives on the scene, they find his coefficient wasn't high enough to raise an alarm. The same man attacks a woman in public, brutally beating her to death with a hammer in front of a crowd and a Psycho-Pass scanner. Later, the team learn that more culprits, wearing the same helmets, rob an armored ca...

As footage of the helmet killings appear on the internet, the helmets are distributed to more criminals who begin committing more horrendous crimes out in the open, prompting bloodthirsty revenge from the public in the name of self-defense. As the MWSPB are sent in to suppress the riots, Kogami deduces that the riots are intended to draw the police away from the Health and Welfare Ministry's Nona ...

As Akane, Kogami, and Shuusei enter the Nona Tower, Makishima intends to act as a diversion at the top of the tower while Guseong reaches the core of the Sibyl System in the hidden basement. Kogami and Akane decide to chase after Makishima to the top of the tower as Shuusei descends to the basement. After descending to the hidden basement, Shuusei has lost connection with the network and discovers...

After Makishima is taken in and the riots are brought under control, Kogami remains curious about how Makishima will be judged, as well as the whereabouts of Shuusei. Later that day, Kasei tells Ginoza that Makishima's case has been taken out of the MWPSB's hands and orders him to investigate Shuusei's whereabouts, much to the ire of both Ginoza and Kogami. Later, Makishima is confronted by Kasei ...

As Ginoza discovers that he is unauthorized to investigate the crash site of Makishima's carrier, Kasei reassigns him on recapturing Makishima and requests that Kogami should be taken off the case. Kogami suspects that something is amiss behind the whole order, believing there is something Kasei is hiding from them. Agreeing with him, Ginoza arranges for Kogami to be transferred to Division 2 who ...

Ginoza, whose Hue is now problematic, eschews intensive therapy in order to work on retrieving Kogami and Makishima. He argues with Masaoka over his "softness," and declares his intention to see his "obsession" through to the end. Kogami, meanwhile, goes to visit Saiga in order to figure out Makishima's next move; the two surmise that Makishima might attempt to meddle with Japan's food supply in o...

The Sibyl System reveals itself to Akane and notes that she understands the necessity of the system, if not its justifiability. Makishima finds the professor who is responsible for the hyper-oats and murders him after finding the information he seeks, taking along the man's fingers and eyeballs as a measure against biometric security. Kogami arrives on the scene not long after and leaves a clue fo...

As Makishima works on reprogramming the virus, both Kogami and the MWPSB arrive at the factory, with Kogami instructing Akane that they need to shut down power to the facility to bypass the security. Prior to arriving, Akane manages to convince the Sibyl System to keep her Dominator on Paralyzer mode with the safety unlocked regardless of Crime Coefficient to use as a trump card against Makishima ...

Kogami and Makishima fight against each other, with Kogami managing to land a hit, but their fight is broken up when Akane arrives on the scene. Instead of arresting Kogami, Akane gives her the modified Dominator so they can both pursue Makishima. Makishima attempts to escape via truck, but Akane manages to get onto it and burst its tire, causing it to crash. With Akane to injured to fight, Kogami...